Mark Ruffalo will star opposite Leonardo DiCaprio in Martin Scorsese's drama Shutter Island, according to The Hollywood Reporter.
In Laeta Kalogridis' adaptation of Dennis Lehane's 2004 novel, Ruffalo will portray U.S. Marshal Chuck Aule, who travels with his new partner (DiCaprio) to the eponymous Massachusetts island in 1954.
As they investigate the disappearance of a patient from a hospital for the criminally insane, they encounter a web of lies, a hurricane and a deadly inmate riot that leaves them trapped on the island.
The film is set to begin shooting in March and will be released some time in 2009.