Universal Pictures had a good weekend, with Despicable Me, its first foray into animated features, lighting up the box office with an estimated $60.1 million in ticket sales. Good news, considering the Steve Carell-voiced picture was an unproven move for the studio, and carried a price tag of about $69 million.

The Twilight Saga: Eclipse held strong at second, dropping only 48.5% to add $33.4 million to its box office to end up with $244 million in worldwide ticket sales so far.

Robert Rodriguez' Predators landed third with an estimated $25.3 million, a decent take, considering the film cost only $40 million to produce.

In fourth place this week, Toy Story 3 held strong with a moderate 27% drop in ticket sales, adding $22 million to its take, for a four-week total of $340.2 million. And rounding out the top 5, The Last Airbender dropped a horrendous 57.5% to add $17.2 million, adding up to a total of $100.2 million, falling short of its $150 million price tag. 

Here's a closer look at the Top 5 this week:

1. Despicable Me - $60,117,000
2. The Twilight Saga: Eclipse - $33,400,000
3. Predators - $25,300,000
4. Toy Story 3 - $22,000,000
5. The Last Airbender - $17,150,000