John C. Reilly voices Wreck-It Ralph, a video game bad guy who leaves his game in search of a life as a hero. Sarah Silverman plays Vanellope, a girl in a video game called Sugar Rush, which Ralph visits on his journey.
The voice cast is rounded out by Jane Lynch (Role Models), Jack McBrayer, Alan Tudyk, Mindy Kaling, Ed O'Neill, Horatio Sanz, and more.
Wreck-It Ralph is directed by experienced TV animation director Rich Moore (The Simpsons, Futurama, Drawn Together). It will hit theaters November 2.