Helena Ayala (Catherine Zeta-Jones) learns that her husband is a major drug dealer. She then positions herself to continue his operations and have the government's chief witness killed to free him from prison.
Javier Rodriguez (Benicio Del Toro) is a Mexican drug agent who finds himself stuck amid corruption, murder and deceit while trying to bring down a Tijuana drug cartel. In "Traffic," we learn that no one gets away clean.
[high on coke] We act like we have all the answers and we're totally invincible, like our parents seem and their parents before them, and I'm sorry, that I have to be the one to say this, but it's fucking bullshit. For instance I know you jack-off thinking about Caroline even though you're supposedly "in love" with Vanessa. Whatever the fuck that means? I mean, what is that convention anyway? We're all this random collection of self-interest, and we just decide that we're gonna walk two by two down the fucking aisle to Noah's ark?