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David Hyde Pierce attended Yale University and originally studied classical piano. However, he was not focused in this major, so he changed it and ended up graduating with a degree in both English and Theatre Arts.
You are probably are most familiar with Pierce from his role on Frasier, however he has played many other characters also!
You may recognize Pierce form his roles in Bright Lights, Big City, Vampire's Kiss, Sleepless in Seattle, Addams Family Values, Wolf, The Mating Habits of the Earthbound Human, Wet Hot American Summer, Full Frontal, Hellboy, and most recently, The Perfect Host.
He has also appeared on television in the shows The Powers That Be and Titus.
In addition, David Pierce has done voice-overs for A Bug's Life, The Tangerine Bear, Osmosis Jones, Treasure Planet, The Amazing Screw-On Head, and The Simpsons.